RNA centre (Miao lab) is a computational biology laboratory, which focuses on the research of RNA structure, function ( RNA structural informatics ) and single-cell omics sequencing. We develop new computaitonal approaches (algorithms, databases, integrated computational workflows) to understand the RNA function at regulation level and structure level.
RNA structural informatics:
Our lab seeks an agile and predictive understanding of how RNAs code for information processing and replication in living systems. We are creating new computational and chemical tools to enable the precise modeling and design of these RNAs.
We have a longstanding interest in understanding global principles of gene regulation and protein-RNA interactions. We use state-of-the-art genomics approaches, including multi-modal single cell genomics and spatial genomics in combination with machine learning methods to advance our knowledge of cells and tissues.
We are looking for passionate Associate Investigators, Postdocs, Assistant Investigators and Research Assistants to join the team (more info) !
15. Sep 2023
Hao Sun is joining the lab as a Research Assistant.
10. Aug 2023
Jie Wu is joining the lab as a Postdoc.
13. Jul 2023
Liangfeng Huang is joining the lab as a Postdoc.
11. Jul 2023
Baowei Huang is joining the lab as a Postdoc.
1. Jun 2023
Jiajun Lin is joining the lab as a Research Assistant.
6. May 2023
Ying Ao will join the lab as a graduate student.
14. Apr 2023
Lahong Xu is joining the lab as a Postdoc.
30. Mar 2023
Recently, Prof. Zhichao Miao and Prof.Jules A Hoffmann collaborated on an article entitled Single Cell Analysis of the Fate of Injected Oncogenic RasV12 Cells in Adult Wild Type Drosophila in the Journal of innate immunity, They have injected dish-cultured oncogenic RasV12 cells into adult male flies and analyzed by single cell transcriptomics their destiny within the host after 11 days.They identified in the preinjection samples and in the 11-day postinjection samples in all 16 clusters of cells, of which 5 disappeared during the experiment in the host,and they hypothesize that this results from a bitter dialogue between the injected cells and the host, while the experiments presented here should contribute to deciphering this dialogue
1. Mar 2023
Yan Liu is joining the lab as a Research Assistant.